Understanding ALS and CTE: What You Need to Know

When Patrick Grange was diagnosed with ALS in 2012, no one could have predicted the impact his case would have on sports medicine research. After his passing, Pat’s brain was donated to Boston University’s CTE Center — and the findings changed everything.

What is ALS?

Amyotrophic lateral sclerosis (ALS), also known as Lou Gehrig’s disease, is a progressive neurodegenerative disease that affects nerve cells in the brain and spinal cord. It leads to loss of muscle control and is ultimately fatal.

Key facts about ALS:

• Approximately 5,000 people in the U.S. are diagnosed with ALS each year
• The average life expectancy after diagnosis is 2-5 years
• There is currently no cure, though treatments can slow progression
• The cause is unknown in most cases

What is CTE?

Chronic traumatic encephalopathy (CTE) is a brain condition associated with repeated head impacts. It can only be definitively diagnosed after death through brain examination.

Patrick’s Case

Patrick Grange became the first American soccer player diagnosed with CTE. His case, published by researchers at Boston University, suggested a potential link between repetitive heading in soccer and brain disease.

This groundbreaking finding has:

• Sparked research into heading safety in soccer
• Led to rule changes limiting heading in youth soccer
• Raised awareness about head injury risks in non-collision sports

What We’re Doing

Through the Patrick Grange Memorial Foundation, we continue to:

1. Fund research at leading institutions studying the ALS-CTE connection
2. Advocate for safer playing practices in youth and amateur sports
3. Educate communities about the signs and risks of head injuries

How You Can Help

• Donate to fund ongoing research
• Share this article to raise awareness
• Contact us to learn more about getting involved

Together, we can honor Pat’s legacy and work toward a world without ALS.